Genetic sequence generates research buzz
The honey bee genome is good news for beekeepers and sting victims
By Helen R. Pilcher - 9 January 2004
A
draft version of the honey bee genome has been made available to the public - a
move that should benefit bees and humans alike.
The honey bee (Apis mellifera) is multi-talented. It produces honey, pollinates
crops and is used by researchers to study human genetics, ageing, disease and
social behaviour. "Without bees and pollination, the entire ecosystem would
crumble," says Richard Gibbs, who led the sequencing effort at the Baylor
College of Medicine, Houston.
Its genome is about one-tenth the size of its human equivalent, containing about
300 million DNA base pairs. Because the genome is relatively small, genes should
be easy to identify, says bee researcher Steve Martin from the University of
Sheffield, UK. Many of these will be similar to their human counterparts, he
says.
The bee genome may also help us understand the genetics of ageing and social
behaviour, says Martin. Queen bees, for example, can live five times as long as
their subordinates. Unpicking their genes may help researchers understand why.
Honey monsters
The genome's publication is good news for beekeepers and victims of bee stings
alike.
Across the globe bees are threatened by a pesticide-resistant mite called
varroa. The bug, which has spread from Asia, weakens the insects, making them
susceptible to fatal infections. "The new information may help researchers
generate varroa-resistant bee strains," says Claire Waring, editor of the
beekeeping journal Bee Craft. Such insects would be healthier and produce more
honey.
It may also help us understand aggressive bee behaviour, says Gibbs. Stroppy
swarms of Africanized bees can attack and kill people and animals. The genome
may reveal the genes linked to bad bee behaviour. "This may help us deal with
the problem," he says.
Researchers have deposited the draft sequence with GenBank, a public database
run by America's National Institutes of Health. It will also be published on
European and Japanese databases.
The project began in 2003, when the US Department of Agriculture and the
National Human Genome Research Institute donated more than US$7 million. This is
the first time that the amassed sequence data have been made publicly available.